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  • Functional Iron Deficiency and Survival on PD

    A 10-year retrospective look at survival examined records from 1,173 PD patients who had normal iron levels, absolute iron deficiency, functional iron deficiency (FID), or high iron levels. Among the group, 77.5% had iron deficiency, and FID, in particular, was linked with an increased risk of all-cause—but not cardiovascular—mortality.

    Read the abstract » | (added 2021-03-09)

    Tags: Mortality, Peritoneal Dialysis, PD

  • Outcomes and Costs of Assisted PD

    As many as half of those who could use PD need assistance to do so, and many countries outside the U.S. offer this. A narrative review found no differences in quality of life, hospitalization, or mortality between PD and in-center HD patients after adjusting for age and frailty. Nurse assistance may result in better technique survival than family assistance. Assisted PD was still significantly less costly than in-center HD in Canada and Western Europe.

    Read the abstract » | (added 2021-03-09)

    Tags: Assisted Peritoneal Dialysis, Barriers, Cost, Hemodialysis, Peritoneal Dialysis, Pd

  • Complications in Planned vs. Unplanned Peritoneal Dialysis Starts

    A metaanalysis of 14 papers totalling 2,401 PD patients looked at the outcomes and safety of unplanned PD starts within 7 days of catheter placement vs. 7-14 days. Early-start PD was linked with more leaks, omental wrap, and—for CAPD—catheter malposition. There were no significant differences in infectious complications, but the risk of transition to HD and mortality were higher. More studies are needed.

    Read the abstract » | (added 2020-11-12)

    Tags: End Stage Kidney Disease, Peritoneal Dialysis, PD

  • Survival Benefit of More HD Hours is Not Sustained After a Switch Back to Standard

    In the ACTIVE Dialysis trial, 200 standard HD patients were randomized to receive usual care (median of 12 hours of HD/week) or extended hours (median of 24 hours of HD/week) for 12 months, with follow up through 60 months. After the 12 months, intervention group participants were switched back to usual care. At 5 years, there was no difference between the groups in all-cause mortality.

    Read the abstract » | (added 2020-10-12)

    Tags: Dialysis, End stage Kidney Disease

  • PD and Bone Mineral Disorders vs. HD

    Body composition, nutritional status, DEXA, and bone mineral disease (BMD) biomarkers were assessed at baseline and one year in 242 ESRD patients starting either PD (n=138) or HD (n=104). Among HD patients, BMD decreased significantly—but not in PD patients. Preservation of BMD was associated with significantly lower all-cause mortality, with cortical bone preservation more predictive than trabecular bone preservation.

    Read the abstract » | (added 2020-09-11)

    Tags: End stage Renal Disease, Bone Mineral Density, Dialysis

  • Aspergillus Peritonitis Review

    Compared to other fungal peritonitis, colonization with aspergillus is more dangerous, and identification is still a challenge. Among 55 cases reported in the literature between 1968 and 2019, the mortality rate was 38.3%, 85.5% had to have their PD catheter removed, and 81.8% of patients had to switch to HD.

    Read the abstract » | (added 2020-09-11)

    Tags: Aspergillus, Mortality, Peritoneal Dialysis, Peritonitis

  • Comorbidities—but not Peritonitis—drove Mortality on PD

    Among 242 Turkish PD patients followed for up to 9 years, age over 65, diabetes, cancer, and heart failure were independent risk factors for death, but surprisingly peritonitis was not.

    Read the abstract » | (added 2020-02-19)

    Tags: Peritoneal Dialysis, Mortality, Patient Survival, Peritonitis, Technique Survival

  • European Patients Live Longer with Extended HD Treatments

    Compared to standard in-center HD, patients from eight European countries who dialyzed for 6+ hours thrice weekly lived longer. Of 142,460 patients, 1,338 did extended HD. Compared to in-center HD (13.5/100 person-years), crude mortality for extended HD (6.0/100 person-years) was significantly better. Overall, those treated with extended treatments were 73% more likely to have survived.

    Read the abstract » | (added 2019-12-10)

    Tags: Survival, Extended hours Hemodialysis, Haemodialysis, ERA EDTA Registry

  • In-center Nocturnal HD: Fewer Complications than PD in Patients with PKD

    An analysis that matched PDK patients who did conventional HD (26) or PD (26) to in-center nocturnal HD (NHD; 13) found no significant difference in mortality—but after a median follow up of 5.5 years, NHD had significantly fewer complications than PD—and higher serum albumin levels as well.

    Read the abstract » | (added 2019-12-10)

    Tags: Polycystic Kidney Disease, Conventional Dialysis, In center Nocturnal HD, Nocturnal Hemodialysis, Mortality

  • Is PD Unwise for Patients with Lupus Nephritis?

    A small study found 92.4% (1 year), 84.7% (3 year) and 67.6% (5 year) patient survival among 28 non-diabetic lupus patients doing PD—compared to 100% (1 year), 93.5% (3 year), and 82.9% (5 year) among 56 controls. While the lupus was not directly associated with mortality, it was a risk factor for PD technique failure, infection, and hospitalizations.

    Read the abstract » | (added 2019-11-16)

    Tags: Patient Survival, Lupus, PD, Mortality, Technique Failure, Infection, Hospitalization