Journal Watch

  1. Home HD - Significantly Better Survival and Transplant Rate

    A Swedish matched cohort study compared the long-term survival of 152 home HD patients with those doing PD (n=456) or standard in-center HD (n=608). Median survival for home HD was significantly better (18.5 years) than PD (15.0) and in-center HD (11.9). Home HD patients were also significantly more likely to have received a transplant.

    Read the abstract » | (added 03/12/2019)

    Tags: Survival, Home Hemodialysis, Institutional Hemodialysis, Peritoneal Dialysis

  2. HOW do AGE’s Cause Peritoneal Fibrosis?

    For years, researchers have known that the advanced glycation endpoints (AGEs) that form when sugar-based PD fluid is made harm the membrane. But, we didn’t know why. Human cell modeling finds that AGEs cause outer layer peritoneal cells (epithelial) to become connective tissue cells (mesenchymal).

    Read the abstract » | (added 03/12/2019)

    Tags: Ag Es, Mesothelial, Epithelial, Stat3

  3. Longer HD Treatments Do Not Make Up for the 2-day “Killer Gap”

    For 20 years, the kidney community has known that death on HD is significantly higher on the day after the 2-day “killer gap.” An analysis of 250+ minutes vs. <200 minutes HD treatments found that even 4.5 hour long treatments thrice weekly did not make the gap less lethal.

    Read the abstract » | (added 03/12/2019)

    Tags: Treatment Time, Interdialytic Interval, Hospitalization, Mortality

  4. Most Cost Effective Dialysis Options: Metaanalysis

    An analysis of 16 economic studies from both high- and low-income countries determined that home dialysis options are less costly and offer comparable—or better—health outcomes than in-center HD. Quality of life concerns were rarely investigated, however.

    Read the abstract » | (added 02/14/2019)

    Tags: Economic Studies, Hd, Cost, Dialysis Options, Health Outcomes

  5. Longitudinal Experience with Remote PD Monitoring

    Patients whose PD was monitored remotely had almost twice the number of APD prescription changes--and significantly fewer nighttime alarms and less need for in-person visits than control subjects, saving both time and money.

    Read the abstract » | (added 02/14/2019)

    Tags: Pd, Remote Monitoring, Apd, Nighttime Alarm, In Person Visit

  6. Fewer Hip Fractures with PD than Standard In-Center HD: Metaanalysis

    Analysis of five cohort studies totalling more than 1.2 million ESRD patients found that those doing HD had a 61% higher risk of hip fracture than those doing PD.

    Read the abstract » | (added 02/14/2019)

    Tags: Hip Fractures, Pd, In Center Hd

  7. Lower Dementia Risk with PD than Standard In-Center HD: Metaanalysis

    An analysis of 15 studies concludes that PD is associated with a lower risk of cognitive decline and dementia than HD--but calls for well-conducted prospective studies.

    Read the abstract » | (added 02/14/2019)

    Tags: Dementia, Pd, In Center Hd, Cognitive Functions

  8. Urgent-start PD Catheter Placement - Surgical vs. Percutaneous

    PD catheter placement does NOT have to be limited to just minimally-invasive percutaneous procedures, suggests a literature review. But, minimizing intraperitoneal pressure for the first 2 weeks IS important.

    Read the abstract » | (added 02/14/2019)

    Tags: Pd, Catheter, Urgent Start, Complications

  9. To Screen or Not to Screen PD Patients for Bacteria: That is the Question

    Does the ISPD guideline for routine use of mupirocin ointment at PD exit sites risk creating mupirocin-resistant organisms? No, finds a surveillance study of 1,175 swabs from 240 patients.

    Read the abstract » | (added 02/14/2019)

    Tags: Mupirocin, Pd, Catheter, Peritonitis, Pseudomonas, Hygiene

  10. Home Dialysis Barriers Examined (Again)

    Since the NKF-KDOQI is a latecomer to the home dialysis party (at least for home HD), they started at the beginning with a conference identifying barriers to starting and keeping patients at home. Not surprisingly, cursory education, and lack of exposure to home options or support for care partners were implicated.

    Read the abstract » | (added 01/11/2019)

    Tags: Home Dialysis, Kdoqi, Barriers, Patient Support