Journal Watch
ISPD Proposes to Remove PD Toxin Clearance Targets
New ISPD Guidelines suggest that the focus of PD should be patient well-being—not lab values. This change would allow more people to do PD, and focusing on relieving uremic symptoms could help determine which solutes really do matter to quality of life.
Read the abstract » | (added 2023-08-16)
Tags: PD, Patient Well being, Lab Values, Uremic Symptoms, Quality Of Life
Home Dialyzor Telehealth Preferences
A small study (n=34) that included surveys and 21 interviews found that 70% of home dialysis patients preferred face-to-face home visits, while 68% had previously had telehealth visits. Knowledge of telehealth was the main perceived barrier, while convenience and flexibility were the main benefits. Non-English speaking patients were at a disadvantage for telehealth.
Read the abstract » | (added 2023-07-17)
Tags: Home Dialysis, Home Visits, Telehealth
Value of an Integrated Home Dialysis Model in the United Kingdom: A Cost-Effectiveness Analysis
This study aimed to determine the lifetime cost-effectiveness of increasing home hemodialysis as a treatment option for patients experiencing peritoneal dialysis technique failure compared with the current standard of care.
Read the abstract » | (added 2023-07-17)
Tags: Cost effective, Home Hemodialysis, Treatment Option, Peritoneal Dialysis Technique Failure
GI Outcomes in PD Trials
A meta-analysis of 61 trials looking at patient-reported GI outcomes of PD mainly found nausea (43% of trials), diarrhea (43%), constipation (34%), abdominal pain (31%) and PD peritonitis (40%). But, only 19% of the available trials reported GI outcomes at all.
Read the abstract » | (added 2023-07-17)
Tags: GI Outcomes, PD, Nausea, Diarrhea, Constipation, Abdominal Pain, Peritonitis
PD vs. Home HD for Severe Infections
In a Finnish study of 536 patients using home dialysis, the risk of a severe infection (C-reactive protein of 100mg/L or higher) in year 1 of CAPD was 35%, APD was 25% and home HD was 11%. Over a 5-year period, compared to home HD, the hazard ratio of severe infection for APD was 2.2 and for CAPD, 2.8. PD peritonitis accounted for the difference.
Read the abstract » | (added 2023-07-17)
Tags: Home Dialysis, Severe Infection, C reactive Protein, CAPD, APD, HD, Home HD, PD Peritonitis
Paradoxical Finding in PD Peritonitis
The common wisdom is that larger patients are at greater risk for PD-associated peritonitis (PDAP). But, a new single-center study of 483 peritonitis episodes in 285 patients suggests that the opposite may be true. A lower value of body surface area was an independent risk factor for peritonitis episodes. (p=0.015).
Read the abstract » | (added 2023-07-17)
Tags: Body Surface Area, PDAP, Metabolism, Nutrition, PD, Peritoneal Dialysis, Peritonitis
Hope Matters in PD
Among 134 patients receiving PD in Hong Kong, those who were working, had a higher income, and were using a cycler for PD had higher hope scores, and there were correlations with age and social support. Higher hope scores were linked with better mental well-being and less severe depression.
Read the abstract » | (added 2023-06-14)
Tags: PD, PD Cycler, Work, Hope Score, Social Support, Mental Well being, Depression
2023 ISPD Catheter Infection Recommendations
The updated recommendations have new definitions and classifications of exit site infection and tunnel infection, and new targets.
Read the abstract » | (added 2023-06-14)
Tags: Catheter, Infection, Exit Site Infection, Tunnel Infection, Antibiotic Treatment
Portable, Wearable, and Implantable Artificial Kidneys
The need to continuously regenerate dialysate is a challenge for all portable, wearable, and implantable kidney replacement therapy options. Sorbent technology is one approach. New membrane materials can remove more uremic toxins than current ones. Combining these membranes with living kidney cells has potential as well.
Read the abstract » | (added 2023-06-14)
Tags: Dialysate, Portable, Wearable, Implantable Kidney, Kidney Replacement Therapy
Pathophysiology of Encapsulating Peritoneal Sclerosis (EPS)
EPS is a rare but often fatal complication of PD. Biopsy findings from Japan suggest that EPS is not sclerosis, but formation of a neo-membrane in response to a peritoneal injury.
Read the abstract » | (added 2023-06-14)
Tags: EPS, Sclerosis, Neo membrane