Journal Watch

  • Safety Study of the PD Automated Wearable Artificial Kidney

    In the AWAK pilot study, 15 participants used up to nine sessions over 72 hours and were then followed for one month. There were no serious adverse events, but 60% of participants had abdominal pain and 47% reported bloating. Median body weights were not significantly different before and after the study. Device enhancements will address ultrafiltration and pain.

    Read the abstract » | (added 2021-06-15)

    Tags: Wearable Kidney, Artificial Kidney, Chronic Kidney Disease, Peritoneal Dialysis

  • PDOPPS Findings of Factors Important to Peritonitis Outcomes

    The Peritoneal Dialysis Outcomes and Practice Patterns Study analyzed factors in the outcomes variations among 1,631 peritonitis episodes in 1,190 patients in seven countries. About 2/3 of the bouts were successfully cured, which was more likely with Gram-positive organisms, automated PD, and use of icodextrin (facility level), aminoglycosides, and ciprofloxacin vs. ceftazidime for Gram-negative organisms.

    Read the abstract » | (added 2021-06-15)

    Tags: Peritoneal Dialysis, Peritonitis, Peritoneal Dialysis And Outcomes Practice Patterns Study

  • PD vs. Standard In-Center HD for Stroke Risk: A 14-year Study

    Of 7,916 ESRD patients with atrial fibrillation between 2001 and 2013, data from 363 PD and 5,302 HD patients were analyzed. At 1 year, 3 years, and 5 years, the participants who used PD had significantly lower risks for outcomes including stroke, major bleeding, and intracranial hemorrhage than those using HD.

    Read the abstract » | (added 2021-06-15)

    Tags: ESRD, End Stage Renal Disease, Atrial Fibrillation, Peritoneal Dialysis, Hemodialysis, Patient Outcomes

  • Home vs. In-center HD Outcomes from a Matched Cohort

    After adjusting for BMI, smoking, race, and comorbidities, home HD came out ahead of in-center HD when 181 home HD patients were matched to 413 using in-center HD. With home HD, the risk of death was significantly less, and phosphate levels were significantly lower. There were no major differences in transplant rates, graft survival, hemoglobin, calcium, or PTH levels.

    Read the abstract » | (added 2021-06-15)

    Tags: Dialysis Modality; End stage Kidney Disease; Haemodialysis, Hemodialysis, Home Haemodialysis, Home Hemodialysis, Mortality

  • The impact of low magnesium levels on heart disease deaths on PD

    Hypomagnesemia is linked with all-cause mortality in HD—but, what about PD? A study classed 1,004 blood tests from PD patients measuring magnesium into one of three groups: <0.7 mmol/L, 0.7-1.2 mmol/L, and >1.2 mmol/L. Those in the lowest magnesium group did have a higher risk of death from both heart and non-heart causes.

    Read the abstract » | (added 2021-05-14)

    Tags: Noncardiovascular Disease, Peritoneal Dialysis, PD

  • PD vs. standard HD for health-related quality of life, and employment

    A DOPPS study analyzed data from 7,771 standard in-center HD and PD patients in six countries. Those from Japan had the highest physical functioning and employment rates—with PD better than HD. The U.S. had the highest mental functioning and lowest employment rates. During one year, physical and mental function did not change much.

    Read the abstract » | (added 2021-05-14)

    Tags: Kidney Disease, Employment, DOPPS

  • How the Ontario Renal Network (ORN) has been trying to grow home dialysis

    ORN started efforts to increase home dialysis use in Ontario in 2012, using a new funding formula based on modality, mandatory informatics, home dialysis coordinator and assisted PD funding, support for urgent start PD, targets for home dialysis rates, a network of clinics committed to home therapies, and frequent leadership meetings. Did they succeed?

    Read the abstract » | (added 2021-05-14)

    Tags: Home Dialysis, Home Haemodialysis, Peritoneal Dialysis, Hd, Pd

  • Measure needed for life participation in PD

    A literature review and metaanalysis of 301 studies identified 42 measures to assess life participation, but most were used in just one study or were not specific to PD. The authors conclude that a new measure is needed.

    Read the abstract » | (added 2021-05-14)

    Tags: Life Participation, Peritoneal Dialysis, Pd

  • U.S. nephrology fellows’ perceptions of their home dialysis training

    To grow home therapies, we must have clinicians who are trained in PD and home HD. A survey of 110 nephrology trainees suggests that we are not there yet. Of the 76 respondents, most were moderately confident about PD principles—but not urgent start PD or catheter insertion. Confidence around home HD was low.

    Read the abstract » | (added 2021-05-14)

    Tags: Home Dialysis, Hd, Home Hemodialysis, Hdd, Peritoneal Dialysis, Pd

  • Metaanalysis: Weighted PD Catheters are Better

    Analysis of data from 20 RCTs and 18 observational studies found no differences between double-cuff vs. single-cuff, swan-neck vs. straight-neck, and coiled-tip vs. straight tip PD catheters. Weighted PD catheters, on the other hand, were linked with significantly lower rates of tunnel infection, migration, drainage failure, cuff extrusion, and complication-related removal.

    Read the abstract » | (added 2021-04-16)

    Tags: Self locating Catheter, Coiled Catheter, Tenckhoff Catheter