Journal Watch

  • PD vs. HD for Quality of Life

    Eleven studies from 2000 to 2019 (N=3,711) comparing PD with in-center HD (ICHD), PD vs. home HD, ICHD vs. self-care ICHD, ICHD vs. home HD, and various home HD modalities with each other were analyzed to determine the impact of modality on quality of life. PD was favored in some domains, while ICHD was favored in others. Home HD was rated significantly higher than ICHD for some domains.

    Read the abstract » | (added 2020-11-12)

    Tags: Dialysis, Dialysis Choice, PD, HD

  • Quanta SC+ Efficacy and Safety

    A human factors test of the Quanta SC+ of 60 patients in the UK (1,333 treatments) using conventional, thrice weekly schedules had no serious adverse events. Ultrafiltration was within acceptable limits.The threshold standardized Kt/V was exceeded in 94% of treatments, and in 97.6% of patients who did not have significantly residual kidney function.

    Read the abstract » | (added 2020-11-12)

    Tags: Chronic Kidney Disease, Hd, Self care Dialysis

  • 24-hour Dietary Recall Less Accurate for Protein Intake Assessment in PD

    Among 50 PD patients, use of protein nitrogen appearance (PNA) revealed levels of protein that ranged from 48.27-67.74 grams per day; median 55.75—while 24-hour dietary estimated the levels at 45.28-87.40; median 61.43 g/day. The authors suggest that proportionality bias may have influenced the results.

    Read the abstract » | (added 2020-10-12)

    Tags: Dialysis Initiation, Dialysate, Peritoneal Dialysis, PD

  • Pilot: Chlorhexidine-impregnated Sponge Dressings to Prevent Exit Site Infections

    In a single-center study, 50 incident PD patients were taught to use a weekly chlorhexidine dressing on their exit sites, and followed for a year. While 12% developed contact dermatitis, 73% found the dressings acceptable. Episodes per patient year of exit-site/tunnel infections and peritonitis were 0.09 and 0.07, respectively, while 1-year technique and patient survival rates were 86% and 96%, respectively.

    Read the abstract » | (added 2020-10-12)

    Tags: Chlorhexidine Dressing, Exit site Infection, Peritoneal Dialysis

  • Physical Activity May Reduce Bone Density in PD

    In a paradoxical finding, 13 women and 21 men on PD who were sedentary had higher BMD than those who were moderately or vigorously physically active. Other aspects of body composition and biochemistry, such as creatinine clearance and triglyceride levels were linked with higher levels of physical activity.

    Read the abstract » | (added 2020-10-12)

    Tags: Body Composition, Bone Density, Muscle Strength

  • Survival Benefit of More HD Hours is Not Sustained After a Switch Back to Standard

    In the ACTIVE Dialysis trial, 200 standard HD patients were randomized to receive usual care (median of 12 hours of HD/week) or extended hours (median of 24 hours of HD/week) for 12 months, with follow up through 60 months. After the 12 months, intervention group participants were switched back to usual care. At 5 years, there was no difference between the groups in all-cause mortality.

    Read the abstract » | (added 2020-10-12)

    Tags: Dialysis, End stage Kidney Disease

  • International Use of PD

    Worldwide PD use is approximately 11%, which varies across the globe, finds a new survey of stakeholders in 182 countries (with 313 respondents from 160 countries). Median PD use was 38.1 per million. Thirty countries, mainly low-income, did not offer PD, while in 69% of countries, PD was the first modality for <10% of incident patients. The range of PD costs passed on to patients was 1-25%, with higher co-pays in South Asia and low-income countries. Patient-reported PD outcomes were rarely measured.

    Read the abstract » | (added 2020-09-11)

    Tags: Epidemiology, Kidney Failure, Peritoneal Dialysis

  • SARS-CoV-2 in PD Effluent

    Analysis of bodily fluids from 3 SARS-CoV-2-infected PD patients found that, while viral load was quite high in nasopharyngeal swabs, none of the PD effluent tested positive, even after dialysate concentration. This suggests that the risk of virus transmission from used PD fluid may be low.

    Read the abstract » | (added 2020-09-11)

    Tags: COVID 19, SARS CoV 2, Peritoneal Dialysis

  • Aspergillus Peritonitis Review

    Compared to other fungal peritonitis, colonization with aspergillus is more dangerous, and identification is still a challenge. Among 55 cases reported in the literature between 1968 and 2019, the mortality rate was 38.3%, 85.5% had to have their PD catheter removed, and 81.8% of patients had to switch to HD.

    Read the abstract » | (added 2020-09-11)

    Tags: Aspergillus, Mortality, Peritoneal Dialysis, Peritonitis

  • Advantages of PD in Primary Glomerulonephritis (PGN)

    A prospective observational study followed all incident PD patients (n=2,243) who had PGN in the Levante registry from 1995 to 2014. Compared to other diagnoses, those with PGN had a significantly lower rate of peritonitis and better mean survival. The authors conclude that “PD has several advantages as a first dialytic treatment, and our results suggest that it is an excellent technique to manage patients with PGN while they await a kidney transplant.”

    Read the abstract » | (added 2020-09-11)

    Tags: Patient Survival, Peritoneal Dialysis, Primary Glomerulonephritis